2014
- Can we use the epigenetic bioactivity of phytochemicals to promote healthy ageing ?
Michael. S. Christodoulou, Adeline Thomas, Stéphane Poulain, Melita Vidakovic, Maija.lahtela-kakkonen, DaumantasMatulis, Philippe Bertrand, Eva Bartova, Christophe Blanquart, Emmanuel Mikros, Nikolas Fokialakis, Daniele Passarella, RachidBenhida and Nadine Martinet.
Med ChemComm, 2014 (in press). - Superacid and thiol-ene reactions for access to psammaplin analogues with HDAC inhibition activities.
El Bahhaj F, Désiré J, Blanquart C, Martinet N, Zwick V, Simões-Pires C, Cuendet M, Grégoire M, Bertrand P.
Tetrahedron,2014 (in press).
December 2014
- [Chemical databases and virtual screening].
Rognan D, Bonnet P.
Med Sci (Paris). 2014 Dec;30(12):1152-60. doi: 10.1051/medsci/20143012019. Epub 2014 Dec 24. French. - Vorinostat-polymer conjugate nanoparticles for Acid-responsive delivery and passive tumor targeting.
Denis I, El Bahhaj F, Collette F, Delatouche R, Gueugnon F, Pouliquen D, Pichavant L, Héroguez V, Grégoire M, Bertrand P, Blanquart C.
Biomacromolecules. 2014 Dec 8;15(12):4534-43. doi: 10.1021/bm501338r. Epub 2014 Nov 7. - Aurones as histone deacetylase inhibitors: identification of key features.
Zwick V, Chatzivasileiou AO, Deschamps N, Roussaki M, Simões-Pires CA, Nurisso A, Denis I, Blanquart C, Martinet N, Carrupt PA, Detsi A, Cuendet M.
Bioorg Med Chem Lett. 2014 Dec 1;24(23):5497-501. doi: 10.1016/j.bmcl.2014.10.019. Epub 2014 Oct 13.
November 2014
- The azaindole framework in the design of kinase inhibitors.
Mérour JY, Buron F, Plé K, Bonnet P, Routier S.
Molecules. 2014 Nov 28;19(12):19935-79. doi: 10.3390/molecules191219935.
October 2014
- Exploring protein kinase conformation using swarm-enhanced sampling molecular dynamics.
Atzori A, Bruce NJ, Burusco KK, Wroblowski B, Bonnet P, Bryce RA.
J Chem Inf Model. 2014 Oct 27;54(10):2764-75. doi: 10.1021/ci5003334. Epub 2014 Sep 17.
September 2014
- Delivery of epidrugs.
el Bahhaj F, Dekker FJ, Martinet N, Bertrand P.
Drug Discov Today. 2014 Sep;19(9):1337-52. doi: 10.1016/j.drudis.2014.03.017. Epub 2014 Mar 25. - CDK11(p58) kinase activity is required to protect sister chromatid cohesion at centromeres in mitosis.
Rakkaa T, Escudé C, Giet R, Magnaghi-Jaulin L, Jaulin C.
Chromosome Res. 2014 Sep;22(3):267-76. doi: 10.1007/s10577-013-9400-x. Epub 2014 Jan 17. - DGKI methylation status modulates the prognostic value of MGMT in glioblastoma patients treated with combined radio-chemotherapy with temozolomide.
Etcheverry A, Aubry M, Idbaih A, Vauleon E, Marie Y, Menei P, Boniface R, Figarella-Branger D, Karayan-Tapon L, Quillien V, Sanson M, de Tayrac M, Delattre JY, Mosser J.
PLoS One. 2014 Sep 18;9(9):e104455. doi: 10.1371/journal.pone.0104455. eCollection 2 - DNMT3L interacts with transcription factors to target DNMT3L/DNMT3B to specific DNA sequences: role of the DNMT3L/DNMT3B/p65-NFκB complex in the (de-)methylation of TRAF1.
Pacaud R, Sery Q, Oliver L, Vallette FM, Tost J, Cartron PF.
Biochimie. 2014 Sep;104:36-49. doi: 10.1016/j.biochi.2014.05.005. Epub 2014 Jun 18.
July 2014
- Genome sequence of a crustacean iridovirus, IIV31, isolated from the pill bug, Armadillidium vulgare.
Piégu B, Guizard S, Yeping T, Cruaud C, Asgari S, Bideshi DK, Federici BA, Bigot Y.
J Gen Virol. 2014 Jul;95(Pt 7):1585-90. doi: 10.1099/vir.0.066076-0. Epub 2014 Apr 10. - Dynamic estrogen receptor interactomes control estrogen-responsive trefoil Factor (TFF) locus cell-specific activities.
Quintin J, Le Péron C, Palierne G, Bizot M, Cunha S, Sérandour AA, Avner S, Henry C, Percevault F, Belaud-Rotureau MA, Huet S, Watrin E, Eeckhoute J, Legagneux V, Salbert G, Métivier R.
Mol Cell Biol. 2014 Jul;34(13):2418-36. doi: 10.1128/MCB.00918-13. Epub 2014 Apr 21. - The actin/MKL1 signalling pathway influences cell growth and gene expression through large-scale chromatin reorganization and histone post-translational modifications.
Flouriot G, Huet G, Demay F, Pakdel F, Boujrad N, Michel D.
Biochem J. 2014 Jul 15;461(2):257-68. doi: 10.1042/BJ20131240.
June 2014
- DNA methylation modulates HRES1/p28 expression in B cells from patients with Lupus.
Fali T, Le Dantec C, Thabet Y, Jousse S, Hanrotel C, Youinou P, Brooks WH, Perl A, Renaudineau Y.
Autoimmunity. 2014 Jun;47(4):265-71. doi: 10.3109/08916934.2013.826207. Epub 2013 Oct 14. - New histone deacetylase inhibitors improve cisplatin antitumor properties against thoracic cancer cells.
Gueugnon F, Cartron PF, Charrier C, Bertrand P, Fonteneau JF, Gregoire M, Blanquart C.
Oncotarget. 2014 Jun 30;5(12):4504-15. - Specific inhibition of DNMT1/CFP1 reduces cancer phenotypes and enhances chemotherapy effectiveness.
Cheray M, Nadaradjane A, Bonnet P, Routier S, Vallette FM, Cartron PF.
Epigenomics. 2014 Jun;6(3):267-75. doi: 10.2217/epi.14.18.
May 2014
- Complete genome sequence of invertebrate iridovirus IIV-25 isolated from a blackfly larva.
Piégu B, Guizard S, Spears T, Cruaud C, Couloux A, Bideshi DK, Federici BA, Bigot Y.
Arch Virol. 2014 May;159(5):1181-5.
April 2014
- Complete genome sequence of invertebrate iridovirus IIV22A, a variant of IIV22, isolated originally from a blackfly larva.
Piégu B, Guizard S, Yeping T, Cruaud C, Couloux A, Bideshi DK, Federici BA, Bigot Y.
Stand Genomic Sci. 2014 Apr 20;9(3):940-7. doi: 10.4056/sigs.5059132. eCollection 2014 Jun 15. - The contribution of epigenetics in Sjögren's Syndrome.
Konsta OD, Thabet Y, Le Dantec C, Brooks WH, Tzioufas AG, Pers JO, Renaudineau Y.
Front Genet. 2014 Apr 3;5:71. doi: 10.3389/fgene.2014.00071. eCollection 2014. Review.
March 2014
- Selective inhibition of BET bromodomain epigenetic signalling interferes with the bone-associated tumour vicious cycle.
Lamoureux F, Baud'huin M, Rodriguez Calleja L, Jacques C, Berreur M, Rédini F, Lecanda F, Bradner JE, Heymann D, Ory B.
Nat Commun. 2014 Mar 19;5:3511. doi: 10.1038/ncomms4511. - The DNMT1/PCNA/UHRF1 disruption induces tumorigenesis characterized by similar genetic and epigenetic signatures.
Pacaud R, Brocard E, Lalier L, Hervouet E, Vallette FM, Cartron PF.
Sci Rep. 2014 Mar 18;4:4230. doi: 10.1038/srep04230. - Receptor-Independent Ectopic Activity of Prolactin Predicts Aggressive Lung Tumors and Indicates HDACi-Based Therapeutic Strategies.
Le Bescont A, Vitte AL, Debernardi A, Curtet S, Buchou T, Vayr J, de Reyniès A, Ito A, Guardiola P, Brambilla C, Yoshida M, Brambilla E, Rousseaux S, Khochbin S.
Antioxid Redox Signal. 2014 Mar 6. [Epub ahead of print]
February 2014
- Complete genome sequence of invertebrate iridovirus IIV30 isolated from the corn earworm, Helicoverpa zea.
Piégu B, Guizard S, Spears T, Cruaud C, Couloux A, Bideshi DK, Federici BA, Bigot Y.
J Invertebr Pathol. 2014 Feb;116:43-7. doi: 10.1016/j.jip.2013.12.007. Epub 2014 Jan 3. - Outcome-based determination of optimal pyrosequencing assay for MGMT methylation detection in glioblastoma patients.
Quillien V, Lavenu A, Sanson M, Legrain M, Dubus P, Karayan-Tapon L, Mosser J, Ichimura K, Figarella-Branger D.
J Neurooncol. 2014 Feb;116(3):487-96. doi: 10.1007/s11060-013-1332-y. Epub 2014 Jan 14.
January 2014
- SHOOT GROWTH1 maintains Arabidopsis epigenomes by regulating IBM1.
Coustham V, Vlad D, Deremetz A, Gy I, Cubillos FA, Kerdaffrec E, Loudet O, Bouché N.
PLoS One. 2014 Jan 3;9(1):e84687. doi: 10.1371/journal.pone.0084687. eCollection 2014. - Peroxisome proliferator-activated receptor γ regulates genes involved in insulin/insulin-like growth factor signaling and lipid metabolism during adipogenesis through functionally distinct enhancer classes.
Oger F, Dubois-Chevalier J, Gheeraert C, Avner S, Durand E, Froguel P, Salbert G, Staels B, Lefebvre P, Eeckhoute J.
J Biol Chem. 2014 Jan 10;289(2):708-22. doi: 10.1074/jbc.M113.526996. Epub 2013 Nov 27.