2016
October 2016
- Epigenetics: DNA methylation signatures in Sjögren syndrome.
Renaudineau Y, Ballestar E.
Nat Rev Rheumatol. 2016 Oct;12(10):565-6. doi: 10.1038/nrrheum.2016.144. No abstract available. PMID: 27627868
August 2016
- Specific Inhibition of DNMT3A/ISGF3γ Interaction Increases the Temozolomide Efficiency to Reduce Tumor Growth.
Cheray M, Pacaud R, Nadaradjane A, Oliver L, Vallette FM, Cartron PF.
Theranostics. 2016 Aug 25;6(11):1988-1999.PMID: 27698935
July 2016
- The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent.
Brenner C, Luciani J, Bizet M, Ndlovu M, Josseaux E, Dedeurwaerder S, Calonne E, Putmans P, Cartron PF, Defrance M, Fuks F, Deplus R.
Oncotarget. 2016 Jul 16. doi: 10.18632/oncotarget.10624. [Epub ahead of print] - miRNA-193a-5p repression of p73 controls Cisplatin chemoresistance in primary bone tumors.
Jacques C, Calleja LR, Baud'huin M, Quillard T, Heymann D, Lamoureux F, Ory B.
Oncotarget. 2016 Jul 29. doi: 10.18632/oncotarget.10950. [Epub ahead of print]
June 2016
- Epigenetic modifications in salivary glands from patients with Sjögren's syndrome affect cytokeratin 19 expression.
Konsta OD, Charras A, Le Dantec C, Kapsogeorgeou E, Bordron A, Brooks WH, Tzioufas AG, Pers JO, Renaudineau Y.
Bull Group Int Rech Sci Stomatol Odontol. 2016 Jun 28;53(1):e01.PMID: 27352422 - Characterization of preneoplastic and neoplastic rat mesothelial cell lines: the involvement of TETs, DNMTs, and 5-hydroxymethylcytosine.
Roulois D, Deshayes S, Guilly MN, Nader JS, Liddell C, Robard M, Hulin P, Ouacher A, Le Martelot V, Fonteneau JF, Grégoire M, Blanquart C, Pouliquen DL.
Oncotarget. 2016 Jun 7;7(23):34664-87. doi: 10.18632/oncotarget.8970.PMID: 27129173 - ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis.
Rodriguez Calleja L, Jacques C, Lamoureux F, Baud'huin M, Tellez Gabriel M, Quillard T, Sahay D, Perrot P, Amiaud J, Charrier C, Brion R, Lecanda F, Verrecchia F, Heymann D, Ellisen LW, Ory B.
Cancer Res. 2016 Jun 1;76(11):3236-51. doi: 10.1158/0008-5472.CAN-15-2317. Epub 2016 Mar 17. - HACE1 is a putative tumor suppressor gene in B-cell lymphomagenesis and is down-regulated by both deletion and epigenetic alterations.
Bouzelfen A, Alcantara M, Kora H, Picquenot JM, Bertrand P, Cornic M, Mareschal S, Bohers E, Maingonnat C, Ruminy P, Adriouch S, Boyer O, Dubois S, Bastard C, Tilly H, Latouche JB, Jardin F.
Leuk Res. 2016 Jun;45:90-100. doi: 10.1016/j.leukres.2016.04.007. Epub 2016 Apr 11.
May 2016
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Tandem virtual screening targeting the SRA domain of UHRF1 identifies a novel chemical tool modulating DNA methylation.
Myrianthopoulos V, Cartron PF, Liutkevičiūtė Z, Klimašauskas S, Matulis D, Bronner C, Martinet N, Mikros E.
Eur J Med Chem. 2016 May 23;114:390-6. doi: 10.1016/j.ejmech.2016.02.043. Epub 2016 Feb 23.
April 2016
- Targeting the epigenetic readers in Ewing sarcoma inhibits the oncogenic transcription factor EWS/Fli1.
Jacques C, Lamoureux F, Baud'huin M, Rodriguez Calleja L, Quillard T, Amiaud J, Tirode F, Rédini F, Bradner JE, Heymann D, Ory B.
Oncotarget. 2016 Apr 26;7(17):24125-40. doi: 10.18632/oncotarget.8214.
March 2016
- Histone Deacetylase Inhibitors Delivery using Nanoparticles with Intrinsic Passive Tumor Targeting Properties for Tumor Therapy.
El Bahhaj F, Denis I, Pichavant L, Delatouche R, Collette F, Linot C, Pouliquen D, Grégoire M, Héroguez V, Blanquart C, Bertrand P.
Theranostics. 2016 Mar 25;6(6):795-807. doi: 10.7150/thno.13725. eCollection 2016.
January 2016
- Cross metathesis with hydroxamate and benzamide BOC-protected alkenes to access HDAC inhibitors and their biological evaluation highlighted intrinsic activity of BOC-protected dihydroxamates.
Zwick V, Nurisso A, Simões-Pires C, Bouchet S, Martinet N, Lehotzky A, Ovadi J, Cuendet M, Blanquart C, Bertrand P.
Bioorg Med Chem Lett. 2016 Jan 1;26(1):154-9. doi: 10.1016/j.bmcl.2015.11.011. Epub 2015 Nov 11.